Cruciferous Vegetables, Isothiocyanates and Indoles

IARC Handbooks of Cancer Prevention Volume 9



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There is evidence that cruciferous vegetables at levels relevant to human intake or more can inhibit neoplastic and preneoplastic responses in experimental animals, mainly when given simultaneously with carcinogens or throughout the experiment. The findings of this Handbook should encourage the promotion of cruciferous vegetable consumption as a part of a diet containing a variety of fruit and vegetables to reduce cancer risk and improve health.

Cover Page
Contents, List of participants, Preface
Chapter 1. Cruciferous vegetables
Chapter 2. Glucosinolates, isothiocyanates and indoles
Chapter 3. Metabolism, kinetics and genetic variation
Chapter 4. Cancer-preventive effects
Chapter 5. Other beneficial effects of cruciferous vegetables, isothiocyanates and indoles
Chapter 6. Carcinogenicity
Chapter 7. Toxic effects
Chapter 8. Summary
Chapter 9. Evaluation
Chapter 10. Recommendations
Appendix & List of abbreviations
Working procedures